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Wed 16 Sept · 20:00

Anderlecht vs Lyon prediction

Follow AnderlechtFollow LyonFollow this match
Round
League Stage - 1
Venue
Lotto Park, Brussels
Referee
Ricardo De Burgos Bengoetxea, Spain

Published by the BetGenius Editorial Desk · Editorial policy

Form

Recent form

Anderlecht
59Average

Last 5 matches · 3W-0D-2L · +5 goal difference

Lyon
53Average

Last 5 matches · 3W-0D-2L · +2 goal difference

Our call

Our verdict

Double Chance
Anderlecht or Draw

BetGenius backs Anderlecht or Draw (Double Chance) at 70% confidence — a solid call. Total goals: Under 2.5 Goals.

70%
Confidence
Solid
Preview

Match preview

Anderlecht kick off their UEFA Europa League league stage campaign by hosting French side Lyon in Brussels. The Belgian outfit enters the fixture in sturdy domestic form, having secured clean sheets in four of their last five outings across all competitions, including a 1-0 victory at KV Mechelen and a 3-0 home triumph against Kairat Almaty.

Lyon arrive following a mixed sequence of results, most recently playing out a goalless stalemate against Paris FC. The visitors have shown defensive resilience on the road, winning 2-0 at Toulouse and drawing 0-0 in Paris, though their overall consistency has been tested across recent fixtures.

With both sides demonstrating compact defensive structures in their recent competitive fixtures, this opening European contest is set to be tightly contested. Anderlecht's home solidity gives them a strong foundation to compete for points from the outset.

Analysis

Key factors

  1. Anderlecht have kept clean sheets in four of their last five matches across all competitions.
  2. Lyon have conceded zero goals across their last two away matches, drawing 0-0 with Paris FC and beating Toulouse 2-0.
  3. Four of Anderlecht's last five competitive fixtures have finished with under 2.5 total goals scored.
  4. Lyon travel without J. Duranville due to a muscle injury alongside several inactive squad members.
Availability

Team news

Anderlecht

  • I. CamaraFoot Injury
  • L. HeyBroken Leg
  • I. KoutsoupiasOff the roster
  • K. SardellaThigh Injury

Lyon

  • L. OpendaLeg Injury
  • M. OuedraogoKnee Injury
  • N. TagliaficoMuscle Injury
  • P. SulcKnee Injury
  • A. HamdaniInactive
Numbers

Statistical comparison

Anderlecht at homeLyon away
4
Played
3
3-1-0
W-D-L
1-1-1
1.5
Scored /game
1
0.3
Conceded /game
0.7
—
Clean sheets
—
—
Failed to score
—
40%
BTTS (last 5)
60%
80%
Over 2.5 (last 5)
100%

Combined scoring rate: 2.5 goals per game (Anderlecht at home plus Lyon away).

Players

Key players this season

Anderlecht

  • E. Llansana2A

Lyon

  • Keito Nakamura2A

League scoring and assist totals for this season — not a predicted lineup. Availability is only shown where team news names the same player.

Table

Table context

Full table →
#TeamPGDPts
9SunderlandPromotion - Europa League (Play Offs: 1/16-finals)3+27
10AZ AlkmaarPromotion - Europa League (Play Offs: 1/16-finals)3+46
11Omonia NicosiaPromotion - Europa League (Play Offs: 1/16-finals)3+16
12LyonPromotion - Europa League (Play Offs: 1/16-finals)3-16
13RennesPromotion - Europa League (Play Offs: 1/16-finals)3+15
14Real SociedadPromotion - Europa League (Play Offs: 1/16-finals)3+54
15Crystal PalacePromotion - Europa League (Play Offs: 1/16-finals)3+34
19Sturm GrazPromotion - Europa League (Play Offs: 1/16-finals)3-24
20NEC NijmegenPromotion - Europa League (Play Offs: 1/16-finals)3-34
21Red Bull SalzburgPromotion - Europa League (Play Offs: 1/16-finals)3-34
22AnderlechtPromotion - Europa League (Play Offs: 1/16-finals)3+13
231899 HoffenheimPromotion - Europa League (Play Offs: 1/16-finals)303
24AC MilanPromotion - Europa League (Play Offs: 1/16-finals)3-13
25Celta Vigo3-13
History

Head-to-head

Full record →
0
Anderlecht
0
Draws
1
Lyon

Lyon have won 1 of the last 1 meeting.

  • 2022-07-16Anderlecht2-3Lyon
BetGenius

Our record in UEFA Europa League

60%59 won from 98 settled predictions (1 void)

Settled results only — every published pick is recorded win or lose. Full track record →

Based on at least 20 settled predictions.
Predictions

1 published market

FeaturedLOST
Double Chance
Anderlecht or Draw
70%
Confidence

Anderlecht have maintained strong form at home, securing clean sheets in their last three matches at Lotto Park across all competitions with results of 3-0 against Kairat Almaty, 1-0 against Kortrijk, and 0-0 against Genk. Lyon have been solid yet cautious away from home, recording a 0-0 draw at Paris FC and a 2-0 win at Toulouse, while dealing with squad absences including J. Duranville. Backing Anderlecht to avoid defeat covers both the home win and the draw in what projects to be a balanced European clash.

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Published September 15, 2026. Form, team news and table context refresh automatically.